SH-PTP2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB:NIH/3T3,Hela |
| Dilution | WB 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human PTPN11 |
| Abbre | PTPN11 |
| Synonyms | BPTP3;CFC;JMML;METCDS;MGC14433;NS1;OTTHUMP00000166107;OTTHUMP00000166108;Protein tyrosine phosphatase 2;Protein tyrosine phosphatase 2C;Protein tyrosine phosphatase non receptor type 11;Protein-tyrosine phosphatase 1D;Protein-tyrosine phosphatase 2C;PTN11;PTP-1D;PTP-2C;PTP1D;PTP2C;PTPN11;SAP2;SH-PTP2;SH-PTP3;SH2 domain containing protein tyrosine phosphatase 2;SHP 2;SHP-2;Shp2;SHPTP2;SHPTP3;Syp;Tyrosine-protein phosphatase non-receptor type 11抗体 |
| Swissprot | |
| Calculated MW | 68kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Neuroscience; Signal Transduction |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
Western Blot analysis of NIH/3T3 and hela cell using SH-PTP2 Polyclonal Antibody at dilution of 1:400
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
