SMARCA4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Hela,MCF-7,A549,Mouse lung Verified Samples in IHC:Human tonsil,Mouse testis,Rat kidney |
| Dilution | WB 1:500-1:2000;IHC 1:200-1:600 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse BRG1 |
| Abbre | SMARCA4 |
| Synonyms | ATP dependent helicase SMARCA4;ATP-dependent helicase SMARCA4;BAF 190;BAF190;BAF190A;Brahma protein like 1;BRG1;BRG1 associated factor 190A;BRG1 protein;BRG1-associated factor 190A;BRM/SWI2 related gene 1;Global transcription activator homologous sequence;global transcription activator snf2l4;Homeotic gene regulator;hSNF2b;Mitotic growth and transcription activator;MRD16;Nuclear protein GRB1;Protein brahma homolog 1;Protein BRG-1;Protein BRG1;RTPS2;SMARC A4;SMARCA4;SMCA4;SNF2;SNF2 beta;SNF2 like 4;SNF2-beta;SNF2B;SNF2L4;SNF2LB;Sucrose nonfermenting like 4;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4;SWI/SNF related;matrix associated;actin dependent regulator of chromatin;subfamily a;member 4;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;SWI2;Transcription activator BRG1抗体 |
| Swissprot | |
| Calculated MW | 185kDa |
| Observed MW | 185kDa |
| Cellular Localization | Nucleus. |
| Concentration | 410 μg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Neuroscience; Stem Cells |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. |
Western Blot analysis of various samples using SMARCA4 Polyclonal Antibody at dilution of 1:750.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using SMARCA4 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse testis using SMARCA4 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat kidney using SMARCA4 Polyclonal Antibody at dilution of 1:200.
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
