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SOCS6 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colon cancer,Human gastric cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human SOCS6
Abbre
SOCS6
Synonyms
CIS-4;CIS4;Cish4;Cytokine inducible SH2 protein 4;Cytokine-inducible SH2 protein 4;HSPC060;SOCS-4;SOCS-6;SOCS4;Socs6;SOCS6;SSI4;STAI4;STAT induced STAT inhibitor 4;STAT4;STATI4;Suppressor of cytokine signaling 4;Suppressor of cytokine signaling 6抗体
Swissprot
Cellular Localization
Cytosol,Plasma Membrane,immunological synapse,Other locations:cytoplasm
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Epigenetics and Nuclear Signaling; Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SOCS6 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SOCS6 Polyclonal Antibody at dilution 1:50


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