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SPDEF Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colon cancer,Human tonsil
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human SPDEF
Abbre
SPDEF
Synonyms
bA375E1.3;PDEF;Prostate derived Ets factor;PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR;Prostate epithelium-specific Ets transcription factor;Prostate specific Ets;Prostate-derived Ets factor;Prostate-specific Ets;PSE;RP11-375E1__A.3;SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR;SAM pointed domain-containing Ets transcription factor;Spdef;SPDEF抗体
Swissprot
Cellular Localization
Nucleus.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SPDEF Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human tonsil tissue using SPDEF Polyclonal Antibody at dilution 1:60


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