TNK2 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human breast cancer,Human ovarian cancer |
| Dilution | IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human TNK2 |
| Abbre | TNK2 |
| Synonyms | Acetate kinase 1;Acetokinase 1;ACK 1;ACK;ACK-1;ACK1;ACK1;Activated Cdc42 associated kinase 1;Activated CDC42 kinase 1;Activated p21cdc42Hs kinase;FLJ44758;FLJ45547;p21cdc42Hs;TNK 2;TNK2;Tyrosine kinase non receptor 2;Tyrosine kinase non receptor protein 2;Tyrosine kinase non-receptor protein 2抗体 |
| Swissprot | |
| Cellular Localization | Cell membrane. Nucleus. Endosome. Cell junction>adherens junction. Cytoplasmic vesicle membrane. The Tyr-284 phosphorylated form is expressed both in the membrane and nucleus. Co-localizes with EGFR on the endosomes. |
| Concentration | 0.5 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. |
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TNK2 Polyclonal Antibody at dilution 1:70
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TNK2 Polyclonal Antibody at dilution 1:70
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
