WNT1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse
- 应用性： WB;IHC-p;IF
| Verified Samples |
Verified Samples in WB:3T3,HT29 Verified Samples in IHC:Mouse brain |
| Dilution | WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Wnt-1 |
| Abbre | Wnt-1 |
| Synonyms | BMND16;INT1;OI15;oncogene Int1;Proto oncogene protein Wnt 1;Proto-oncogene Int-1 homolog;Proto-oncogene Wnt-1;Wingless type MMTV integration site family member 1;wingless-type MMTV integration site family;member 1 (oncogene INT1);Wnt 1;wnt1;WNT1抗体 |
| Swissprot | |
| Calculated MW | 41kDa |
| Observed MW | 45kDa |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Stem Cells |
| Conjugation | Unconjugated |
| Background | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. |
Western Blot analysis of 3T3, HT-29 cells using WNT1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse brain using WNT1 Polyclonal Antibody at dilution of 1:50
