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ZAK Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human gastric cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human ZAK
Abbre
ZAK  
Synonyms
AZK;Cervical cancer suppressor gene 4 protein;HCCS 4;HCCS-4;HCCS4;Human cervical cancer suppressor gene 4 protein;Leucine zipper and sterile alpha motif containing kinase;Leucine zipper- and sterile alpha motif-containing kinase;Mitogen activated protein kinase kinase kinase MLT;Mitogen-activated protein kinase kinase kinase MLT;Mixed lineage kinase 7;Mixed lineage kinase related kinase;Mixed lineage kinase related kinase MRK beta;Mixed lineage kinase with a leucine zipper and a sterile alpha motif;Mixed lineage kinase-related kinase;MLK 7;MLK like mitogen activated protein triple kinase;MLK related kinase;MLK-like mitogen-activated protein triple kinase;MLK-related kinase;MLK7;Mlklak;MLT;MLTK;MRK;Sterile alpha motif and leucine zipper containing kinase AZK;Sterile alpha motif- and leucine zipper-containing kinase AZK;Zak抗体
Swissprot
Cellular Localization
Cytoplasm. Nucleus. Translocates to the nucleus upon ultraviolet B irradiation.
Concentration
1.2 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal Transduction
Conjugation
Unconjugated
Background
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ZAK Polyclonal Antibody at dilution of 1:100(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZAK Polyclonal Antibody at dilution of 1:100(×200)


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