Human IL-6(Interleukin 6) ELISA Kit
人白介素6(IL-6)酶联免疫吸附测定试剂盒
| 规格： | / 96T / 48T / 96T*5 |
| 价格： | / ￥2400 / ￥1650 / ￥10200 |
货号：E-EL-H6156
反应性: 人
检测范围: 1.56~100 pg/mL
灵敏度: 0.94 pg/mL
用途
该试剂盒用于体外定量检测人中IL-6浓度
检测原理
本试剂盒采用双抗体夹心ELISA法。用抗人IL-6抗体包被于酶标板上，实验时样品或标准品中的人IL-6会与包被抗体结合，游离的成分被洗去。依次加入生物素化的抗人IL-6抗体和辣根过氧化物酶标记的亲和素。抗人IL-6抗体与结合在包被抗体上的人IL-6结合、生物素与亲和素特异性结合而形成免疫复合物，游离的成分被洗去。加入显色底物(TMB)，TMB在辣根过氧化物酶的催化下呈现蓝色，加终止液后变成黄色。用酶标仪在450nm波长处测OD值，IL-6浓度与OD450值之间呈正比，通过绘制标准曲线计算出样品中IL-6的浓度。
| 反应类型 | 夹心法 |
| 规格 | 96T |
| 反应时间 | 3.5h |
| 反应性 | 人 |
| 检测方法 | Colormetric |
| 检测范围 | 1.56—100 pg/mL |
| 灵敏度 | 0.94 pg/mL |
| 样本体积 | 100μL |
| 样本类型 |
特异性
可检测样本中的人IL-6，且与其它相关蛋白无明显交叉反应。
重复性
板内，板间变异系数均<10%。
典型数据
由于实验操作条件的不同（如操作者、移液技术、洗板技术和稳定条件等），标准曲线的OD值会有所差异。以下数据和曲线仅供参考，实验者需根据自己的实验建立标准曲线。
| (pg/mL) | O.D | Average | Corrected |
|---|---|---|---|
| 100 | 2.564 2.612 |
2.588 | 2.499 |
| 50 | 1.786 1.83 |
1.808 | 1.719 |
| 25 | 1.004 0.968 |
0.986 | 0.897 |
| 12.5 | 0.51 0.538 |
0.524 | 0.435 |
| 6.25 | 0.303 0.291 |
0.297 | 0.208 |
| 3.13 | 0.207 0.179 |
0.193 | 0.104 |
| 1.56 | 0.141 0.147 |
0.144 | 0.055 |
| 0 | 0.082 0.096 |
0.089 | -- |
精密度
板内精密度:低浓度样本,中浓度样本和高浓度样本分别在1块板子上检测20次。
板间精密度:低浓度样本,中浓度样本和高浓度样本分别在3块板子上检测20次。
| Intra-assay Precision | Inter-assay Precision | |||||
|---|---|---|---|---|---|---|
| Sample | 1 | 2 | 3 | 1 | 2 | 3 |
| n | 20 | 20 | 20 | 20 | 20 | 20 |
| Mean (pg/mL) |
4.98 | 9.90 | 47.86 | 5.13 | 8.95 | 45.89 |
| Standard
deviation |
0.29 | 0.44 | 2.32 | 0.33 | 0.44 | 1.40 |
| C V (%) | 5.78 | 4.46 | 4.85 | 6.49 | 4.91 | 3.05 |
回收率
分别往5个不同样本中添加已知浓度的目标蛋白，做回收实验，得出回收率范围和平均回收率。
| Sample Type | Range (%) | Average Recovery (%) |
|---|---|---|
| Serum (n=5) | 88-101 | 93 |
| EDTA plasma (n=5) | 93-103 | 98 |
| Cell culture media (n=5) | 92-104 | 98 |
线性
分别往5个样本中添加已知浓度的目标蛋白，做回收实验，得出回收率范围及平均回收率。将5个样本分别稀释2倍，4倍，8倍，16倍做回收实验，得出回收率范围及平均回收率。
| Serum (n=5) | EDTA plasma (n=5) | Cell culture media (n=5) | ||
|---|---|---|---|---|
| 1:2 | Range (%) | 89-101 | 95-106 | 90-104 |
| Average (%) | 95 | 100 | 95 | |
| 1:4 | Range (%) | 84-96 | 96-108 | 86-101 |
| Average (%) | 90 | 101 | 93 | |
| 1:8 | Range (%) | 87-98 | 89-105 | 87-100 |
| Average (%) | 93 | 96 | 93 | |
| 1:16 | Range (%) | 85-101 | 88-102 | 89-103 |
| Average (%) | 92 | 96 | 95 |
试剂盒组成及保存
未拆封的试剂盒可在4℃保存一周；如果一周以后才使用试剂盒，请拆开试剂盒按照下表中的条件分别保存各组分。
| 中文名称 | 英文名称 | 规格 | 保存条件 |
|---|---|---|---|
| ELISA酶标板(可拆卸) | Micro ELISA Plate(Dismountable) | 8 孔×12 条 | -20℃，可存放6个月 |
| 冻干标准品 | Reference Standard | 2 支 | |
| 浓缩生物素化抗体(100×) | Concentrated Biotinylated Detection Ab | 1支 120 μL | |
| 浓缩HRP酶结合物(100×) | Concentrated HRP Conjugate | 1支 120 μL | -20℃(避光)，可存放6个月 |
| 标准品&样品稀释液 | Reference Standard & Sample Diluent | 1瓶 20 mL | 4℃.可存放6个月 |
| 生物素化抗体稀释液 | Biotinylated Detection Ab Diluent | 1瓶 14 mL | |
| 酶结合物稀释液 | HRP Conjugate Diluent | 1瓶 14 mL | |
| 浓缩洗涤液(25×) | Concentrated Wash Buffer (25×) | 1瓶 30 mL | |
| 底物溶液(TMB) | Substrate Reagent | 1瓶 10 mL | 4℃(避光) |
| 反应终止液 | Stop Solution | 1瓶 10 mL | 4℃ |
| 封板覆膜 | Plate Sealer | 5 张 | |
| 产品说明书 | Product Description | 1 份 | |
| 质检报告 | Certificate of Analysis | 1 份 |
说明：所有试剂瓶盖须旋紧以防止蒸发和微生物的污染。
试剂体积以实际发货版说明书为准。相关试剂在分装时会比标签上标明的体积稍多一些，请在使用时量取而非直接倒出。
试验所需自备物品
- 1. 酶标仪(450nm波长滤光片)
- 2. 高精度移液器，EP管及一次性吸头：0.5-10 μL, 2-20 μL, 20-200 μL, 200-1000 μL
- 3. 37℃恒温箱，双蒸水或去离子水
- 4. 吸水纸
操作步骤
|
|
1.对应板孔中加入100μL标准品工作液或样本，37℃孵育90分钟 |
| 2.弃掉板内液体后，立即加入100μL生物素化抗体工作液，37℃孵育60分钟 | |
| 3.弃掉板内液体，洗板3次 | |
| 4.每孔加入100μL HRP酶结合物工作液，37℃孵育30分钟，弃掉板内液体，洗板5次 | |
| 5.每孔加入90μL底物溶液，37℃孵育15分钟 | |
| 6.每孔加入50μL终止液 | |
| 7.立即在450nm波长下读数，处理数据 |
客户发表文献
- 文献: KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1
样品类型: Cell culture supernatant - 文献: Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD
样品类型: Serum - 文献: Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy
样品类型: Cell culture supernatant - 文献: Double-Layer Nanofibrous Sponge Tube via Electrospun Fiber and Yarn for Promoting Urethral Regeneration
样品类型: Human foreskin fibroblasts (HFFs),HSF cell - 文献: A SCID mouse-human lung xenograft model of SARS-CoV-2 infection
样品类型: Tissue homogenate - 文献: Light-Mediated 3D Printing of Micro-Pyramid-Decorated Tailorable Wound Dressings with Endogenous Growth Factor Sequestration for Improved Wound Healing
样品类型: THP-1 cell - 文献: High mobility group box 1 derived mainly from platelet microparticles exacerbates microvascular obstruction in no reflow
样品类型: Human cardiac microvascular endothelial cells (HCMECs) - 文献: Biodegradable MoSe2-polyvinylpyrrolidone nanoparticles with multi-enzyme activity for ameliorating acute pancreatitis
样品类型: serum - 文献: Combined effect of polystyrene microplastics and bisphenol A on the human embryonic stem cells-derived liver organoids: The hepatotoxicity and lipid accumulation
样品类型: liver organoids (LOs) - 文献: Chronic exposure to Cytolethal Distending Toxin (CDT) promotes a cGAS-dependent type I interferon response
样品类型: HeLa-S3 cells - 文献: Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line
样品类型: HMC3 cell - 文献: Physicochemical properties and protective effects on UVA-induced photoaging in Hs68 cells of Pleurotus ostreatus polysaccharides by fractional precipitation
样品类型: Hs68 cell - 文献: Red Blood Cells-Derived Vesicles for Delivery of Lipophilic Drug Camptothecin
样品类型: THP-1 cells - 文献: METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner
样品类型: RPE cell - 文献: Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling pathway
样品类型: HepG2 cell - 文献: MicroRNA-101-3p Downregulates TLR2 Expression, Leading to Reduction in Cytokine Production by Treponema pallidum–Stimulated Macrophages
样品类型: plasma,THP-1 cell - 文献: HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism
样品类型: serum - 文献: Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury
样品类型: serum - 文献: Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial.
样品类型: plasma - 文献: Stiff substrates inhibit collagen accumulation via integrin α2β1, FAK and Src kinases in human atrial fibroblast and myofibroblast cultures derived from patients with aortal stenosis
样品类型: cardiac fibroblast - 文献: Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study
样品类型: serum - 文献: TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.
样品类型: THP-1 monocytes - 文献: Lactobacillus plantarum CCFM1143 Alleviates Chronic Diarrhea via Inflammation Regulation and Gut Microbiota Modulation: A Double-Blind, Randomized, Placebo-Controlled Study
样品类型: serum - 文献: Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis
- 文献: Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia
样品类型: HMC3 cells - 文献: Rational design of a prodrug to inhibit self-inflammation for cancer treatment
样品类型: Serum,Cell culture supernatant(dendritic cells,4T1 cell - 文献: Mechanisms of Antitumor Invasion and Metastasis of the Marine Fungal Derivative Epi-Aszonalenin A in HT1080 Cells
样品类型: HT1080 cell - 文献: The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.
样品类型: HCMEC/D3 cell,U87MG cell - 文献: Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo
样品类型: THP-1 cells - 文献: In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts
- 文献: Fermented Taiwanofungus camphoratus Extract Ameliorates Psoriasis-Associated Response in HaCaT Cells via Modulating NF-𝜅B and mTOR Pathways
- 文献: Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness
样品类型: hASMCs cells - 文献: miR-122–5p regulates hepatocytes damage caused by BaP and DBP co-exposure through SOCS1/STAT3 signaling in vitro
样品类型: L02 cell - 文献: GSDMD-miR-223-NLRP3 axis involved in B(a)P-induced inflammatory injury of alveolar epithelial cells
样品类型: A549 cell - 文献: Whole grain germinated brown rice regulates intestinal immune homeostasis and gastrointestinal hormones in type 2 diabetic patients—a randomized control trial
样品类型: serum - 文献: Comparative Study of the Pharmacological Properties and Biological Effects of Polygonum aviculare L. herba Extract-Entrapped Liposomes versus Quercetin-Entrapped Liposomes on Doxorubicin-Induced Toxicity on HUVECs
样品类型: HUVEC - 文献: In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes
样品类型: HaCaT cell - 文献: Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo
样品类型: NP cells - 文献: Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets.
样品类型: serum - 文献: Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro
样品类型: MH7A cell - 文献: Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling
样品类型: NP cell - 文献: EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma
样品类型: Tissue homogenate - 文献: Alteration in Gut Microbiota Associated with Zinc Deficiency in School-Age Children
样品类型: serum - 文献: The Effects of a Single Versus Three Consecutive Sessions of Football Training on Postprandial Lipemia: a Randomized, Controlled Trial in Healthy, Recreationally Active Males
样品类型: serum - 文献: Silenced SNHG1 Inhibited Epithelial-Mesenchymal Transition and Inflammatory Response of ARPE-19 Cells Induced by High Glucose
样品类型: ARPE-19 cell - 文献: Inflammation and Insulin Resistance in a Group of Sub-Saharan African Women with Polycystic Ovary Syndrome
样品类型: plasma - 文献: Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells
样品类型: U937 cell - 文献: Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease
样品类型: plasma - 文献: STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway
样品类型: ARPE-19 cell - 文献: Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function
样品类型: CaCO2 cells，HT‐29 cell - 文献: METTL3 Promotes Activation and Inflammation of FLSs Through the NF-κB Signaling Pathway in Rheumatoid Arthritis
样品类型: synovial - 文献: Fontan protein‐losing enteropathy is associated with advanced liver disease and a proinflammatory intestinal and systemic state
样品类型: Plasma - 文献: A novel glyceroglycolipid from brown algae Ishige okamurae improve photoaging and counteract inflammation in UVB-induced HaCaT cells
样品类型: HaCaT cells - 文献: Comparison study of Beninese and Chinese herbal medicines in treating COVID-19
样品类型: BEAS-2B cell - 文献: Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function
样品类型: Cell culture supernatant - 文献: TLR3-/4-Priming Differentially Promotes Ca 2+ Signaling and Cytokine Expression and Ca 2+ -Dependently Augments Cytokine Release in hMSCs
样品类型: Cell culture supernatant - 文献: CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D
样品类型: Cell culture supernatant(BeWo cells (CCL-98,ATCC)) - 文献: Silk fibroin-alginate based beads for human mesenchymal stem cell differentiation in 3D
样品类型: THP-1 cells - 文献: Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo
样品类型: HFFs cells,HSFs cells - 文献: GLUT3 as an Intersection of Glycerophospholipid Metabolism and the Innate Immune Response to Candida albicans
样品类型: THP-1 cells - 文献: The classic signalling and trans‐signalling of interleukin‐6 are both injurious in podocyte under high glucose exposure
样品类型: Serum - 文献: Downregulation of p300/CBP-associated factor inhibits cardiomyocyte apoptosis via suppression of NF-κB pathway in ischaemia/reperfusion injury rats
样品类型: myocardial tissue,blood - 文献: A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of gut microbiota and relief from chronic constipation
样品类型: serum - 文献: Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis
样品类型: Serum - 文献: Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils
样品类型: Cell culture supernatant - 文献: miR-93-5p-Containing Exosomes Treatment Attenuates Acute Myocardial Infarction-Induced Myocardial Damage
样品类型: serum - 文献: The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium
样品类型: plasma,cerebrospinal fluid - 文献: CircVAPA contributes to hyper-proliferation and inflammation of keratinocytes through miR-125b-5p/sirt6 axis in psoriasis
样品类型: HaCaT cells - 文献: Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure
样品类型: Cell culture supernatant - 文献: Relationship between 25 Hydroxyvitamin D, Overweight/Obesity Status, Pro-Inflammatory and Oxidative Stress Markers in Patients with Type 2 Diabetes: A Simplified Empirical Path Model
样品类型: serum - 文献: Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells
样品类型: Cell culture supernatant - 文献: PM2.5 organic extract mediates inflammation through the ERβ pathway to contribute to lung carcinogenesis in vitro and vivo
样品类型: Cell culture supernatant - 文献: Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages: Implications for Coronavirus Disease 2019 (COVID-19) Therapy
样品类型: THP-1 cell - 文献: Flexible Gold Electrode Array for Multiplexed Immunoelectrochemical Measurement of Three Protein Biomarkers for Prostate Cancer
样品类型: Serum - 文献: Notch down-regulation and inflammatory cytokines and RANKL overexpression involvement in peri-implant mucositis and peri-implantitis: A cross-sectional study
样品类型: peri-implant crevicular fluid - 文献: MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation
样品类型: U87 cell - 文献: Aconiti lateralis radix praeparata total alkaloids exert anti-RA effects by regulating NF-κB and JAK/STAT signaling pathways and promoting apoptosis.
样品类型: MH7A cell - 文献: Effect of fructooligosaccharide on endothelial function in CKD patients: a randomized controlled trial
样品类型: serum - 文献: Multifunctional barrier membranes promote bone regeneration by scavenging H2O2, generating O2, eliminating inflammation, and regulating immune response
样品类型: periodontal ligament stem cells (PDLSCs) - 文献: The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial
样品类型: serum - 文献: Minimally-invasive stone removal in urinary calculi patients during pregnancy: clinical therapeutic effects and low complications
样品类型: serum - 文献: Long non-coding RNA H19 as a diagnostic marker in peripheral blood of patients with sepsis
样品类型: Serum - 文献: Effect of levetiracetam in combination with topiramate on immune function, cognitive function, and neuronal nutritional status of children with intractable epilepsy
样品类型: serum - 文献: Lycium barbarum polysaccharide-glycoprotein promotes osteogenesis in hPDLSCs via ERK activation
样品类型: hPDLSCs - 文献: LncRNA FLG-AS1 Mitigates Diabetic Retinopathy by Regulating Retinal Epithelial Cell Inflammation, Oxidative Stress, and Apoptosis via miR-380-3p/SOCS6 Axis
样品类型: ARPE-19 cell - 文献: CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway
样品类型: HaCaT cell - 文献: Identification of polycystic ovary syndrome from blood serum using hormone levels via Raman spectroscopy and multivariate analysis
样品类型: serum - 文献: A functional polymorphism at the miR‑491‑5p binding site in the 3'‑untranslated region of the MMP‑9 gene increases the risk of developing ventilator‑associated pneumonia
样品类型: peripheral blood - 文献: LncRNA MEG3 ameliorates NiO nanoparticles-induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway
样品类型: A549 cell - 文献: Limonin ameliorates acute pancreatitis by suppressing JAK2/STAT3 signaling pathway
样品类型: serum - 文献: Effects of non‐surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trial
样品类型: saliva - 文献: Changes in Allergenicity of Ovalbumin in Vitro and in Vivo on Conjugation with Quercetin
样品类型: Serum,Cell culture supernatant - 文献: Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil
样品类型: Plasma - 文献: Biochemical investigation of human exposure to aflatoxin M1 and its association with risk factors of diabetes mellitus
样品类型: serum - 文献: NRF2 -617 C/A Polymorphism Impacts Proinflammatory Cytokine Levels, Survival, and Transplant-Related Mortality After Hematopoietic Stem Cell Transplantation in Adult Patients Receiving Busulfan-Based Conditioning Regimens
样品类型: plasma - 文献: Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis
样品类型: Cell culture supernatant - 文献: Elevated leptin levels in temporomandibular joint osteoarthritis promote proinflammatory cytokine IL‐6 expression in synovial fibroblasts
样品类型: Cell culture supernatant - 文献: Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis
样品类型: tuberculous pleural effusion - 文献: Expansion of GARP-Expressing CD4+CD25−FoxP3+ T Cells and SATB1 Association with Activation and Coagulation in Immune Compromised HIV-1-Infected Individuals in South Africa
样品类型: Plasma - 文献: Low-dose 5-aza-2′-deoxycytidine protects against early renal injury by increasing klotho expression
样品类型: Serum,HK-2 cell - 文献: CircTHBS1 facilitates the progression of interstitial cystitis depending on the regulation of miR-139-5p/MFN2 axis
样品类型: serum - 文献: Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways
样品类型: MH7A cell - 文献: Red blood cell transfusion induces abnormal HIF-1α response to cytokine storm after adult cardiac surgery
样品类型: serum - 文献: Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusion
样品类型: pleural fluid - 文献: Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway
样品类型: gingival crevicular fluid (GCF),Human gingival fibrobla - 文献: Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs
样品类型: HUVECs cells - 文献: The stiffness‐controlled release of interleukin‐6 by cardiac fibroblasts is dependent on integrin α2β1
样品类型: Cell culture supernatant - 文献: Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis
样品类型: Cell culture supernatant - 文献: LncRNA SNHG5 regulates cell apoptosis and inflammation by miR-132/PTEN axis in COPD
样品类型: Cell culture supernatant - 文献: Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States
样品类型: serum - 文献: ILF2 Contributes to Hyperproliferation of Keratinocytes and Skin Inflammation in a KLHDC7B-DT-Dependent Manner in Psoriasis
样品类型: keratinocytes - 文献: Kernelized k-Local Hyperplane Distance Nearest-Neighbor Model for Predicting Cerebrovascular Disease in Patients With End-Stage Renal Disease
样品类型: serum - 文献: IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF-κB and IL-6/STAT3 Signaling Pathway
样品类型: Cell culture supernatant - 文献: Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer
样品类型: PC3 cell,HSF cell - 文献: Cardiovascular Disease Prediction by Machine Learning Algorithms Based on Cytokines in Kazakhs of China
样品类型: blood - 文献: Comparison of cognitive impairments with lipid profiles and inflammatory biomarkers in unipolar and bipolar depression
样品类型: serum - 文献: Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats
样品类型: serum - 文献: Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms
样品类型: Cell culture supernatant - 文献: Moesin Is a Novel Biomarker of Endothelial Injury in Sepsis
样品类型: Cell culture supernatant(HMECs) - 文献: Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro
样品类型: Cell culture supernatant - 文献: Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF-κB/STAT3 Activation in Ox-LDL-Treated HUVECs
样品类型: Cell culture supernatant - 文献: CALML6 Controls TAK1 Ubiquitination and Confers Protection against Acute Inflammation
样品类型: Cell culture supernatant - 文献: Potential Therapeutic Activity of Berberine in Thyroid-Associated Ophthalmopathy: Inhibitory Effects on Tissue Remodeling in Orbital Fibroblasts
样品类型: Orbital fibroblasts (OFs) - 文献: Modulatory Effect of Diosmin and Diosmetin on Metalloproteinase Activity and Inflammatory Mediators in Human Skin Fibroblasts Treated with Lipopolysaccharide
样品类型: human fibroblast cell - 文献: Arsenic trioxide improves Treg and Th17 balance by modulating STAT3 in treatment-naïve rheumatoid arthritis patients
样品类型: PBMCs cells - 文献: Altered kynurenine pathway metabolism in patients with ankylosing spondylitis
样品类型: serum - 文献: PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis
样品类型: Serum - 文献: Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR- Functional Module of Autophagy in Rheumatoid Arthritis
样品类型: rheumatoid arthritis (RA) fibroblast-like synoviocytes - 文献: MiR-942-5p alleviates septic acute kidney injury by targeting FOXO3.
样品类型: Cell culture supernatant - 文献: The association of the quality of sleep with proinflammatory cytokine profile in inflammatory bowel disease patients
样品类型: serum - 文献: Role of CD36 rs1761667 AA genotype in the expression of inflammatory cytokines and Parkinson’s disease progression: A case-control study in a northern Han Chinese population
样品类型: plasma - 文献: Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis
样品类型: serum - 文献: LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever
样品类型: plasma - 文献: Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance
样品类型: serum - 文献: IL-16 regulates macrophage polarization as a target gene of mir-145-3p
样品类型: Cell lysate - 文献: A role for serum cytokines and cell adhesion molecules in the non‑invasive diagnosis of colorectal cancer
样品类型: serum - 文献: Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism
样品类型: HepG2 cells - 文献: TSG attenuates LPC‐induced endothelial cells inflammatory damage through notch signaling inhibition
样品类型: Cell culture supernatant - 文献: Inflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy
样品类型: serum - 文献: LncRNA PMS2L2 protects ATDC5 chondrocytes against lipopolysaccharide-induced inflammatory injury by sponging miR-203
样品类型: Cell culture supernatant - 文献: Effect of Ramadan diurnal fasting on visceral adiposity and serum adipokines in overweight and obese individuals
样品类型: Serum - 文献: Oxidative Burst of Circulating Neutrophils Following Traumatic Brain Injury in Human
样品类型: Plasma - 文献: Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia
样品类型: serum - 文献: Transcriptome analysis of eutopic endometrial stromal cells in women with adenomyosis by RNA-sequencing
样品类型: A-EuESCs,N-ESCs - 文献: Nintedanib ameliorates oxidized low-density lipoprotein -induced inflammation and cellular senescence in vascular endothelial cells
样品类型: HUVECs - 文献: Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes
样品类型: HaCaT cell - 文献: Circ_0001897 regulates high glucose-induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-29c-3p/transforming growth factor beta 2 axis
样品类型: Human retinal microvascular endothelial cell (HRECs) - 文献: Carvedilol activates nuclear factor E2-related factor 2/ antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose
样品类型: ARPE-19 cell - 文献: Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs)
样品类型: Human nasal epithelial cells (hNECs) - 文献: The development of an ultra-sensitive electrochemical immunosensor using a PPyr-NHS functionalized disposable ITO sheet for the detection of interleukin 6 in real human serums
样品类型: serum - 文献: DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathway
样品类型: THP-1 cells - 文献: ADSC-conditioned media elicit an ex vivo anti-inflammatory macrophage response
样品类型: Serum,Cell culture medium - 文献: The first cloned echinoderm tumor necrosis factor receptor from Holothuria leucospilota: Molecular characterization and functional analysis
样品类型: Cell culture supernatant - 文献: Comparison of delta-tocotrienol and alpha-tocopherol effects on hepatic steatosis and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: A randomized double-blind active-controlled trial
样品类型: serum - 文献: Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced injury in human tubule epithelial cells by regulating miR-93-5p/TXNIP axis
样品类型: Cell culture supernatant - 文献: Cul4a attenuates LPS-induced acute kidney injury via blocking NF-kB signaling pathway in sepsis
样品类型: HK-2 cell - 文献: Iron Status in Newly Diagnosed β-Thalassemia Major: High Rate of Iron Status due to Erythropoiesis Drive
样品类型: Serum - 文献: Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast‐like synoviocytes through AKT/FOXO1 signaling
样品类型: rheumatoid arthritis (RA) fibroblast-like synoviocytes - 文献: The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study
样品类型: serum - 文献: Association between pro-inflammatory cytokines in cerebrospinal fluid and headache in patients with aneurysmal subarachnoid hemorrhage
样品类型: cerebrospinal fluid (CSF) - 文献: The Role of Plasma Interleukin-6 Levels on Atherosclerotic Cardiovascular Disease and Cardiovascular Mortality Risk Scores in Javanese Patients with Chronic Kidney Disease
样品类型: plasma - 文献: NLRP6 Induces Lung Injury and Inflammation Early in Brucella and Influenza Coinfection
样品类型: lung tissues - 文献: Nomogram Based on Cytokines for Cardiovascular Diseases in Xinjiang Kazakhs
样品类型: plasma - 文献: Grape Seed Proanthocyanidin Extract Inhibits Human Esophageal Squamous Cancerous Cell Line ECA109 via the NF-κB Signaling Pathway
样品类型: ECA109 cells - 文献: Bradykinin/bradykinin 1 receptor promotes brain microvascular endothelial cell permeability and proinflammatory cytokine release by downregulating Wnt3a
样品类型: serum,hBMECs - 文献: Nec-1 Attenuates Neurotoxicity Induced by Titanium Dioxide Nanomaterials on Sh-Sy5y Cells Through RIP1
样品类型: SH-SY5Y cell - 文献: Ethanolic extract of Kaempferia parviflora interrupts the mechanisms-associated rheumatoid arthritis in SW982 culture model via p38/STAT1 and STAT3 pathways
样品类型: Cell culture supernatant - 文献: Expression of Nrf2 protein in serum of patients with rheumatoid arthritis: A novel indicator for disease activity and disease prognosis
样品类型: serum - 文献: strain FP10
样品类型: Cell culture supernatant - 文献: Does the TMPRSS6 C > T Polymorphism Modify the Endurance Training Effects on Hematological Parameters?
样品类型: serum - 文献: Impact of Lipophilic Versus Hydrophilic Statins on the Clinical Outcome and Biomarkers of Remodeling in Heart Failure Patients: A Prospective Comparative Randomized Study
样品类型: serum - 文献: Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro
样品类型: Wound drainage fluid - 文献: Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children
样品类型: Serum - 文献: Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways
样品类型: Serum - 文献: Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles
样品类型: A549 cell - 文献: Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein
样品类型: Serum - 文献: MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD
样品类型: Serum,Cell culture supernatant - 文献: Interleukin-6, undercarboxylated osteocalcin, and brain-derived neurotrophic factor responses to single and repeated sessions of high-intensity interval exercise
样品类型: plasma - 文献: Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma
样品类型: THP-1 cell - 文献: The liver X receptor agonist T0901317 reduces the inflammation of alveolar epithelial cells induced by polyhexamethylene guanidine through inhibition of the NFκB signaling pathway
样品类型: A549 cell - 文献: Possible causes of atherosclerosis: lncRNA COLCA1 induces oxidative stress in human coronary artery endothelial cells and impairs wound healing
样品类型: HCAECs - 文献: Advanced platelet-rich fibrin promotes the paracrine function and proliferation of adipose-derived stem cells and contributes to micro-autologous fat transplantation by modulating HIF-1α and VEGF
样品类型: adipose-derived stem cell (ASCs) - 文献: Mammalian Ste20-like kinase 4 inhibits the inflammatory response in Aspergillus fumigatus keratitis
样品类型: Cell lysate - 文献: Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice
样品类型: Cell culture supernatant - 文献: IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro
样品类型: Cell culture supernatant - 文献: Clonorchis sinensis Co-infection Could Affect the Disease State and Treatment Response of HBV Patients
样品类型: Serum,Cell culture supernatant - 文献: Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome
样品类型: serum - 文献: Silencing of UCA1 Protects Against MPP+-Induced Cytotoxicity in SK-N-SH Cells via Modulating KCTD20 Expression by Sponging miR-423-5p
样品类型: Cell culture supernatant - 文献: Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits
样品类型: Cell culture supernatant - 文献: The effect of different dietary ratios of arginine, methionine, and lysine on the performance, carcass traits, and immune status of turkeys
样品类型: Plasma - 文献: Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome
样品类型: serum - 文献: Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users:
样品类型: Plasma - 文献: Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway
样品类型: Cell culture supernatant - 文献: Auto-reactivity against gut bacterial peptides in patients with late-onset diabetes
样品类型: Serum - 文献: Correlation of Inflammation and Coagulation Markers with the Incidence of Deep Vein Thrombosis in Cancer Patients with High Risk of Thrombosis
样品类型: plasma - 文献: Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-β 1 in mice
样品类型: Tissue homogenate - 文献: Functional characterisation of Holothuria leucospilota Fas-associated death domain in the innate immune-related signalling pathways:
样品类型: Cell culture supernatant - 文献: Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia
样品类型: salivary - 文献: Galectin-3, IL-1A, IL-6, and EGF Levels in Corneal Epithelium of Patients With Recurrent Corneal Erosion Syndrome
样品类型: Tissue homogenate - 文献: A Self-Representation-Based Fuzzy SVM Model for Predicting Vascular Calcification of Hemodialysis Patients
样品类型: serum - 文献: Association of the IRAK4 rs4251545 genetic polymorphism with severity of enterovirus-71 infection in Chinese children
样品类型: plasma - 文献: Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis
样品类型: serum - 文献: Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial
样品类型: blood - 文献: Roles and mechanisms of NRG1 in modulating the pathogenesis of NAFLD through ErbB3 signaling in hepatocytes (NRG1 modulates NAFLD through ErbB3 signaling)
样品类型: Cell culture supernatant - 文献: MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1
样品类型: VEC - 文献: Evaluation of the relationship between pentraxin 3 (PTX3) rs2305619 (281A/G) and rs1840680 (1449A/G) polymorphisms and the clinical course of COVID-19
样品类型: blood - 文献: Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19
样品类型: serum - 文献: Leptin induces IL-6 and IL-8 expression through leptin receptor Ob-Rb in human dental pulp fibroblasts
样品类型: Cell culture supernatant - 文献: Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes
样品类型: Cell culture supernatant - 文献: A case of asthma with Behcet’s disease: successful treatment with omalizumab and its effects on recurrent aphthous lesions
样品类型: Serum - 文献: Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology
样品类型: chondrocytes - 文献: C reactive protein and enzymatically modified LDL cooperatively promote dendritic cell-mediated T cell activation
样品类型: Cell culture supernatant - 文献: Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells
样品类型: Cell lysate - 文献: Study of Metal-Metal Interactions and Their Biomarkers Using an Intestinal Human Cell Line
样品类型: Cell lysate - 文献: Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial
样品类型: serum - 文献: MicroRNA‑16 regulates lipopolysaccharide‑induced inflammatory factor expression by targeting TLR4 in normal human bronchial epithelial cells
样品类型: NHBE cells - 文献: Mediators of extracellular matrix degradation and inflammation: A new team of possible biomarkers for oral squamous cell carcinoma stage
样品类型: Oral cancer tissue - 文献: Mangiferin inhibits hypoxia/reoxygenation‑induced alveolar epithelial cell injury via the SIRT1/AMPK signaling pathway
样品类型: A549 cell - 文献: Comparison of safety, effectiveness and serum inflammatory factor indexes of Saccharomyces boulardii versus Bifidobacterium triple viable in treating children with chronic diarrhea: a randomized trial
样品类型: serum - 文献: LncRNA PMS2L2 downregulates miR-24 through methylation to suppress cell apoptosis in ulcerative colitis
样品类型: HCnEpCs - 文献: Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis
样品类型: Chondrocytes - 文献: Assessment of chemokine and cytokine signatures in patients with dengue infection: A hospital-based study in Kolkata, India
样品类型: Serum - 文献: Serum profile of cytokines and their genetic variants in metabolic syndrome and healthy subjects: a comparative study
样品类型: serum - 文献: Exosomes derived from human umbilical cord mesenchymal stem cells alleviate acute liver failure by reducing the activity of the NLRP3 inflammasome in macrophages
样品类型: Serum - 文献: Interleukin-6 in Cerebrospinal Fluid Small Extracellular Vesicles as a Potential Biomarker for Prognosis of Aneurysmal Subarachnoid Haemorrhage
样品类型: Cerebrospinal Fluid - 文献: Adhesion molecules as diagnostic and severity biomarkers in pediatric community-acquired pneumonia
样品类型: Whole Blood,Serum - 文献: XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485
样品类型: Serum - 文献: Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles
样品类型: Cell culture supernatant - 文献: The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1 β Signaling Axis
样品类型: GES-1 cell - 文献: Upregulated NORAD is implicated in apoptosis, inflammation, and oxidative stress in ulcerative colitis through the nuclear factor-κappaB signaling
样品类型: human normal colonic mucosal cells (FHCs) - 文献: The effects of blood purification combined with antibiotics on extravascular lung water index, inflammatory factors, and prognosis of patients with severe acute pancreatitis complicated with acute respiratory distress syndrome.
样品类型: blood - 文献: Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis: a randomized trial.
样品类型: serum - 文献: CFNAs of RBCs affect the release of inflammatory factors through the expression of CaMKIV in macrophages
样品类型: macrophages - 文献: Predictors of coronary artery calcification and its association with cardiovascular events in patients with chronic kidney disease
样品类型: blood - 文献: Immune Cell and Biochemical Biomarkers in Advanced Laryngeal Cancer:
样品类型: serum - 文献: Correlation of Ionized Magnesium with the Parameters of Oxidative Stress as Potential Biomarkers in Patients with Anxiety and Depression: A Pilot Study:
样品类型: serum - 文献: The Anti-Inflammatory Effect of Smilax china L. Extract on LPS-Stimulated THP-1 via Downregulation of MAPK and NF-κB Signaling Pathway
样品类型: THP-1 cells - 文献: Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197
样品类型: Human Umbilical Vein Endothelial Cells (HUVECs) - 文献: Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.
样品类型: Human nasal epithelial cell (hNECs) - 文献: Effect of Thymosin on Inflammatory Factor Levels, Immune Function, and Quality of Life in Lung Cancer Patients Undergoing Radical Thoracoscopic Surgery
样品类型: Serum - 文献: PLD4 promotes M1 macrophages to perform antitumor effects in colon cancer cells
样品类型: macrophage - 文献: Circ_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke
样品类型: SK-N-SH cells - 文献: Inhibition of microRNA-665 Alleviates Septic Acute Kidney Injury by Targeting Bcl-2
样品类型: HK-2 cell - 文献: Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota
样品类型: Plasma,Serum - 文献: Long non-coding RNA MEG3 regulates CSE-induced apoptosis and inflammation via regulating miR-218 in 16HBE cells
样品类型: Cell culture supernatant - 文献: Plasma concentration of ZCCHC14 contributes to prognostic efficacy in intracerebral hemorrhage patients.
样品类型: Plasma - 文献: The effect of conventional versus electronic cigarette use on treatment outcomes of peri-implant disease
样品类型: Saliva - 文献: Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1–7) upregulation
样品类型: Cell culture supernatant,Serum - 文献: Role of the long non-coding RNA, SPRR2C, based on an in vitro psoriatic keratinocyte cell model
样品类型: Ker-CT cell,HaCaT cell - 文献: High anti-human cytomegalovirus antibody levels are associated with the progression of essential hypertension and target organ damage in Han Chinese population
样品类型: Serum - 文献: Depot-specific inflammation with decreased expression of ATM2 in white adipose tissues induced by high-margarine/lard intake
样品类型: Cell culture supernatant - 文献: Periodontal Ligament Stem Cells Reverse the High Glucose Level-Induced Inflammatory State of Macrophages
样品类型: THP-1 cell - 文献: Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology
样品类型: human histiocytic lymphoma (U-937) cell - 文献: Carotid intima-media thickness and serum proinflammatory cytokine levels in rosacea patients without cardiovascular risk factors
样品类型: Serum - 文献: Fluorometholone inhibits high glucose-induced cellular senescence in human retinal endothelial cells:
样品类型: human retinal endothelial cell - 文献: Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients
样品类型: BEAS-2B cells - 文献: Association of PAR-2 Gene Polymorphisms with the Inflammatory Response and Susceptibility to Knee Osteoarthritis in the Chinese Han Population
样品类型: Synovia - 文献: Inhibition of miR‑27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells
样品类型: Cell culture supernatant - 文献: Blockade of 146b‑5p promotes inflammation in atherosclerosis‑associated foam cell formation by targeting TRAF6
样品类型: macrophages - 文献: Effect of laparoscopic sleeve gastrectomy on renal function in obese patients
样品类型: Serum,Urine - 文献: Frequency of interleukin-6 rs1800795 (-174G/C) and rs1800797 (-597G/A) polymorphisms in COVID-19 patients in Turkey who develop macrophage activation syndrome
样品类型: serum - 文献: MicroRNA-124 alleviates hyperoxia-induced inflammatory response in pulmonary epithelial cell by inhibiting TLR4/NF-κB/CCL2
样品类型: Beas2B cells - 文献: Risk factors for medication-related osteonecrosis of the jaw and salivary IL-6 IN cancer patients
样品类型: Saliva - 文献: Role of miR‑589‑3p in human lumbar disc degeneration and its potential mechanism
样品类型: Cell culture supernatant - 文献: N‑methyl pyrrolidone promotes ankle fracture healing by inhibiting inflammation via suppression of the mitogen‑activated protein kinase signaling pathway
样品类型: peripheral blood - 文献: Anti‑inflammatory effect of Resolvin D1 on LPS‑treated MG‑63 cells Corrigendum in /10.3892/etm.2019.8021
样品类型: Serum - 文献: Short‑term efficacy and safety of prednisone in herpes zoster and the effects on IL‑6 and IL‑10
样品类型: serum - 文献: Effects of propofol combined with remifentanil anesthesia on the NO, endothelin and inflammatory cytokines in the plasma of patients with liver cirrhosis during the perioperative period
样品类型: Plasma - 文献: Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Murine Model: Protective Effect of Cyclosporine-A
样品类型: Serum - 文献: Regulatory role and mechanism of the inhibition of the Mcl-1 pathway during apoptosis and polarization of H37Rv-infected macrophages
样品类型: Cell culture supernatant - 文献: Sex difference in IL-6 modulation of cognition among Chinese individuals with major depressive disorder
样品类型: Serum - 文献: A comparison of effects of scalp nerve block and local anesthetic infiltration on inflammatory response, hemodynamic response, and postoperative pain in patients undergoing craniotomy for cerebral aneurysms: a randomized controlled trial
样品类型: plasm - 文献: Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses
样品类型: Cell culture supernatant - 文献: miR-1287-5p upregulation inhibits the EMT and pro-inflammatory cytokines in LPS-induced human nasal epithelial cells (HNECs)
样品类型: HNECs cells - 文献: Maternal omega-3 polyunsaturated fatty acids supplementation in pregnancy decreases MMP-1 levels in breastmilk: a cross-sectional study
样品类型: Milk - 文献: Assessment of incidence of cerebral vascular diseases and prediction of stroke risk in chronic obstructive pulmonary disease patients using multimodal biomarkers
样品类型: serum - 文献: Systematically transplanted human gingiva‑derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis
样品类型: Serum - 文献: Curcumin affects ox‑LDL‑induced IL‑6, TNF‑α, MCP‑1 secretion and cholesterol efflux in THP‑1 cells by suppressing the TLR4/NF‑κB/miR33a signaling pathway
样品类型: Cell culture supernatant - 文献: Changes in expression of serum chemokine CXCL13 and IL-6 after hip replacement, and the relationship with lower limb vein thrombus
样品类型: Serum - 文献: Application of dexmedetomidine-assisted intravertebral anesthesia in hip replacement and its influence on T-lymphocyte subsets
样品类型: serum - 文献: Are Serum Interleukin 6 and Surfactant Protein D Levels Associated with the Clinical Course of COVID-19?
样品类型: Plasma - 文献: Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression
样品类型: Cell culture medium - 文献: A comparative study of autologous rectus fascia pubovaginal sling surgery and synthetic transobturator vaginal tape procedure in treatment of women with urodynamic stress urinary incontinence
样品类型: blood - 文献: TLR4/NF-κB signaling pathway gene single nucleotide polymorphisms alter gene expression levels and affect ARDS occurrence and prognosis outcomes
样品类型: plasma - 文献: A case-control study on the relationship between miRNAs single nucleotide polymorphisms and sepsis risk
样品类型: Serum - 文献: An unusual case of iron deficiency anemia is associated with extremely low level of transferrin receptor
样品类型: serum - 文献: Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-κB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children
样品类型: Serum - 文献: Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response
样品类型: Serum - 文献: Study of association of varicose veins and inflammation by inflammatory markers:
样品类型: Plasma - 文献: Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells
样品类型: Cell culture supernatant - 文献: Nec-1 attenuates inflammation and cytotoxicity induced by high glucose on THP-1 derived macrophages through RIP1
样品类型: Cell culture supernatant - 文献: The effects of aerobic exercise and sertraline on pro-inflammatory indices and amelioration of neurotrophic factors in patients who have undergone CABG
样品类型: plasma,serum - 文献: The Association of Complements, TGF-β, and IL-6 with Disease Activity, Renal Damage, and Hematological Activity in Patients with Naïve SLE
样品类型: serum - 文献: Production of Inflammatory Mediators in Conditioned Medium of Adipose Tissue-Derived Mesenchymal Stem Cells (ATMSC)-Treated Fresh Frozen Plasma
样品类型: Adipose Tissue-Derived Mesenchymal Stem Cells (ATMSC) - 文献: Potential and Alternative Bioactive Compounds from Brown Agaricus bisporus Mushroom Extracts for Xerosis Treatment
样品类型: HaCaT cells - 文献: Long-Term Resistance–Endurance Combined Training Reduces Pro-Inflammatory Cytokines in Young Adult Females with Obesity
样品类型: serum - 文献: Evaluation of the relationship of serum vitamin D levels in COVID-19 patients with clinical course and prognosis.
样品类型: blood - 文献: Association between Interleukin-6 rs1800795 Polymorphism and Serum Interleukin-6 Levels and Full-Term Neonatal Sepsis
样品类型: serum - 文献: The role of zonulin in the pathogenesis of diabetic retinopathy
样品类型: serum - 文献: Oxidative stress index can be a new marker related to disease severity in COVID-19
样品类型: serum - 文献: Clinical efficacy and inflammatory factors in knee osteoarthritis with glucosamine hydrochloride plus meloxicam
样品类型: serum - 文献: TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes
样品类型: Cell culture supernatant - 文献: Interleukin 8 as predictive factor for response to chemotherapy in colorectal cancer patients
样品类型: serum - 文献: Applied value of monitoring serum hepcidin in differential diagnosis of infection versus tumor fevers
样品类型: Plasma
