TGF β Receptor I Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70130
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | AAT 5,AAT5,Activin A receptor type II like kinase 53kDa,Activin A receptor type II like kinase,53kD,Activin A receptor type II like protein kinase of 53kD,activin A receptor type II-like kinase,53kDa,activin A receptor type II-like protein kinase of 53kD,Activin receptor like kinase 5,Activin receptor-like kinase 5,ACVRLK 4,ACVRLK4,ALK 5,ALK-5,ALK5,LDS1A,LDS2A,MSSE,Serine/threonine protein kinase receptor R4,Serine/threonine-protein kinase receptor R4,SKR 4,SKR4,TbetaR I,TbetaR-I,TGF beta receptor type 1,TGF beta receptor type I,TGF beta type I receptor,TGF-beta receptor type I,TGF-beta receptor type-1,TGF-beta type I receptor,TGFBR 1,TGFBR1,TGFBR1 protein,TGFR 1,TGFR-1,TGFR1,TGFR1,Transforming growth factor beta receptor 1,Transforming growth factor beta receptor I (activin A receptor type II like kinase,53kD),Transforming growth factor beta receptor I,transforming growth factor,beta receptor 1,transforming growth factor,beta receptor I (activin A receptor type II-like kinase,53kD),Transforming growth factor-beta receptor type I,TGF β Receptor I抗体 |
| Swissprot | P36897,Q64729,P80204 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse TGFβR1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 0.9 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Found in all tissues examined, most abundant in placenta and least abundant in brain and heart. Expressed in a variety of cancer cell lines.Highest expression level in decidua |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
客户发表文献
- 文献: Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas
样品类型: retinas,Human Umbilical Vein Endothelial Cells (HUVECs)
