14-3-3 epsilon Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12585
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC,ELISA
Overview
| Synonyms | 14 3 3 E,14 3 3 epsilon,14 3 3E,14-3-3 protein epsilon,14-3-3E,1433E,Epididymis luminal protein 2,FLJ45465,FLJ53559,HEL2,KCIP 1,KCIP1,MDCR,MDS,Mitochondrial import stimulation factor L subunit,Protein kinase C inhibitor protein1,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,epsilon,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,epsilon polypeptide,Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide,YWHAE,YWHAE抗体 |
| Swissprot | P62258 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human YWHAE |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 0.8 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. |
Images
Western Blot analysis of Human brain malignant glioma and laryngocarcinoma tissue using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:1300
Immunohistochemistry of paraffin-embedded Human colon cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human ovarian cancer using 14-3-3 epsilon Polyclonal Antibody at dilution of 1:60
