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AFP Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10000

宿主: Rabbit

反应性: H

应用: WB,IHC,ELISA

  • 详情
  • Overview

    Synonyms Afp,AFPD,Alpha fetoglobulin,Alpha fetoprotein,Alpha fetoprotein precursor,Alpha-1-fetoprotein,Alpha-fetoglobulin,Alpha-fetoprotein,alpha-fetoprotein,Hereditary persistence of,included,FETA,FETA,Hereditary persistence of alpha fetoprotein,HPAFP,AFP抗体
    Swissprot P02771
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human AFP
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:50-1:200;
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted.
    Tissue specificity Plasma. Synthesized by the fetal liver and yolk sac.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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