AFP Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-10000
宿主: Rabbit
反应性: H
应用: WB,IHC,ELISA
Overview
Synonyms | Afp,AFPD,Alpha fetoglobulin,Alpha fetoprotein,Alpha fetoprotein precursor,Alpha-1-fetoprotein,Alpha-fetoglobulin,Alpha-fetoprotein,alpha-fetoprotein,Hereditary persistence of,included,FETA,FETA,Hereditary persistence of alpha fetoprotein,HPAFP,AFP抗体 |
Swissprot | P02771 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human AFP |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Tissue specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |