BRAF Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70237
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | FLJ95109,94 kDa B raf protein,B raf 1,B Raf proto oncogene serine threonine protein kinase,B Raf proto oncogene,serine/threonine kinase,B RAF1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF 1,BRAF,BRAF,BRAF1,cRmil,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,NS7,Oncogen BRAF,oncogene BRAF1,p94,Proto-oncogene B-Raf,Proto-oncogene c-Rmil,RAFB 1,RAFB1,RMIL,Serine/threonine-protein kinase B-raf,v raf murine sarcoma viral oncogene homolog B,v raf murine sarcoma viral oncogene homolog B1,v-Raf murine sarcoma viral oncogene homolog B1,BRAF抗体 |
| Swissprot | P28028 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse B-Ra |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800; |
| Concentration | 0.74 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Cell membrane. Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. |
| Tissue specificity | Highest expression level in pineal body |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded mouse kidney using BRAF Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded mouse testis using BRAF Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat brain using BRAF Polyclonal Antibody at dilution of 1:300.
