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CD45 Monoclonal Antibody

规格: / 20μL / 60μL / 120μL
价格: / ¥580 / ¥1420 / ¥2310

货号:E-AB-22009

宿主: Mouse

反应性: H

应用: WB,IHC-p

  • 详情
  • Overview

    Synonyms B220,CD 45,CD45,CD45 antigen,CD45R,GP180,L-CA,LCA,Leukocyte common antigen,loc,Ly-5,LY5,Ly5,homolog of,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,Protein tyrosine phosphatase,receptor type C,protein tyrosine phosphatase,receptor type,C,Protein tyrosine phosphatase,receptor type,c polypeptide,Ptprc,PTPRC,Receptor-type tyrosine-protein phosphatase C,T200,T200 glycoprotein,T200 leukocyte common antigen,CD45抗体
    Swissprot P08575
    Source Mouse
    Reactivity Human
    Immunogen Synthetic Peptide
    Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-300;
    Concentration 1mg/mL
    Clonality Monoclonal

    Properties

    Cellular localization Membrane
    Clone No Clone:3H3
    Isotype IgG
    Purification Protein A purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.4
    Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. 
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