CD45 Monoclonal Antibody
规格: | / 20μL / 60μL / 120μL |
价格: | / ¥580 / ¥1420 / ¥2310 |
货号:E-AB-22009
宿主: Mouse
反应性: H
应用: WB,IHC-p
Overview
Synonyms | B220,CD 45,CD45,CD45 antigen,CD45R,GP180,L-CA,LCA,Leukocyte common antigen,loc,Ly-5,LY5,Ly5,homolog of,Lyt-4,OTTHUMP00000033813,OTTHUMP00000033816,OTTHUMP00000033817,OTTHUMP00000038574,Protein tyrosine phosphatase receptor type c polypeptide,Protein tyrosine phosphatase,receptor type C,protein tyrosine phosphatase,receptor type,C,Protein tyrosine phosphatase,receptor type,c polypeptide,Ptprc,PTPRC,Receptor-type tyrosine-protein phosphatase C,T200,T200 glycoprotein,T200 leukocyte common antigen,CD45抗体 |
Swissprot | P08575 |
Source | Mouse |
Reactivity | Human |
Immunogen | Synthetic Peptide |
Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-300; |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Cellular localization | Membrane |
Clone No | Clone:3H3 |
---|---|
Isotype | IgG |
Purification | Protein A purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. |
Images
Western Blot analysis of Hela cells using CD45 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.