CK-19 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-31146
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF,ELISA
Overview
| Synonyms | 40 kDa keratin intermediate filament,CK 19,CK-19,CK19,Cytokeratin 19,Cytokeratin-19,K19,K1C19,K1CS,Keratin 19,Keratin type I 40 kD,Keratin type I 40kD,Keratin type I cytoskeletal 19,Keratin,type I cytoskeletal 19,Keratin,type I,40 kd,Keratin-19,KRT19,MGC15366,Cytokeratin 19抗体 |
| Swissprot | P08727 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from the Internal region of human Cytokeratin 19 |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF,ELISA |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000;ELISA,,1:10000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Tissue specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
Images
Western Blot analysis of HY926 cells using CK-19 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CK-19 Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver tissue using CK-19 Polyclonal Antibody at dilution of 1:200.
