COX4I1 Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22002
宿主: Mouse
反应性: H,M,R
应用: WB,IHC-p,IF
Overview
| Synonyms | AL024441,COX 4,COX IV 1,COX IV,COX IV-1,Cox4,COX41,Cox4a,COX4B,COX4I1,COX4I2,COX4L2,COXIV,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1 mitochondrial,Cytochrome c oxidase subunit 4 isoform 1,mitochondrial,Cytochrome C Oxidase subunit IV,Cytochrome c oxidase subunit IV isoform 1,Cytochrome c oxidase subunit IV isoform 2 (lung),Cytochrome c oxydase subunit 4,dJ857M17.2,MGC105470,MGC72016,COX IV抗体 |
| Swissprot | P13073 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:1000-3000;IHC,,1:50-300;IF,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Mitochondrion inner membrane. |
| Tissue specificity | Ubiquitous. |
| Clone No | Clone:2D4 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
| Background | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. |
Images
Western Blot analysis of Hela cells using COX4I1 Monoclonal Antibody at dilution of 1) 1:2000 2) 1:5000.
Immunohistochemistry of paraffin-embedded Rat kidney tissue using COX4I1 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Mouse kidney tissue using COX4I1 Monoclonal Antibody at dilution of 1:200.
客户发表文献
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样品类型: Antibody - 文献: Stretching magnitude–dependent inactivation of AKT by ROS led to enhanced p53 mitochondrial translocation and myoblast apoptosis
样品类型: Tissue homogenate
