DAN Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11421
宿主: Rabbit
反应性: H,M,R
应用: IHC,ELISA
Overview
| Synonyms | D1S1733E,DAN,DAN domain family member 1,DAND 1,DAND1,Differential screening selected gene aberrant in neuroblastoma,MGC8972,NB,NBL 1,Neuroblastoma candidate region suppression of tumorigenicity 1,Neuroblastoma suppression of tumorigenicity 1,Neuroblastoma suppressor of tumorigenicity 1,NO 3,NO3,Zinc finger protein DAN,NBL1抗体 |
| Swissprot | P41271 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human NBL1 |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Most abundant in normal lung and meningioma. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. |
