FGG Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40412
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | FGG, Fibrinogen gamma chain, Fibrinogen gamma polypeptide,FGG抗体 |
Swissprot | Q8VCM7 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Mouse Fibrinogen gamma chain protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:3000;IHC,,1:100-1:300; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. |
Images
Western Blot analysis of Rat liver and Mouse liver using FGG Polyclonal Antibody at dilution of 1:2000
Immunohistochemistry of paraffin-embedded Human liver using FGG Polycloanl Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human placenta using FGG Polycloanl Antibody at dilution of 1:200