FKBP5 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17966
宿主: Rabbit
反应性: H
应用: WB,IHC,ELISA
Overview
Synonyms | 51 kDa FK506 binding protein 5,51 kDa FK506 binding protein,51 kDa FK506-binding protein,51 kDa FKBP,54 kDa progesterone receptor associated immunophilin,54 kDa progesterone receptor-associated immunophilin,AIG 6,AIG6,Androgen regulated protein 6,Androgen-regulated protein 6,FF1 antigen,FK506 binding protein 5,FK506-binding protein 5,FKBP 5,FKBP 51,FKBP 54,FKBP-5,FKBP-51,FKBP5,FKBP5,FKBP54,HSP90 binding immunophilin,HSP90-binding immunophilin,MGC111006,OTTHUMP00000016268,P54,Peptidyl prolyl cis trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP5,Peptidylprolyl cis trans isomerase,PPIase,PPIase FKBP5,Ptg 10,Ptg10,Rotamase,T cell FK506 binding protein,FKBP5抗体 |
Swissprot | Q13451 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human FKBP5 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:300;ELISA,,1:5000-1:10000; |
Concentration | 1.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants. |
Images
Western blot analysis of A172 Hela HepG2 K562 and PC3 cell lysates using FKBP5 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FKBP5 Polyclonal Antibody at dilution of 1:50(×200)