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FN1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10003

宿主: Rabbit

反应性: H,M,R

应用: IHC,ELISA

  • 详情
  • Overview

    Synonyms CIG,Cold insoluble globulin,Cold-insoluble globulin,DKFZp686F10164,DKFZp686H0342,DKFZp686I1370,DKFZp686O13149,ED B,Fibronectin 1,FINC,FINC,FN,FN1,FNZ,GFND,GFND2,LETS,Migration stimulating factor,MSF,Ugl-Y3,FN1抗体
    Swissprot P02751
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human FN1
    Application IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution IHC,,1:50-1:200;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted, extracellular space, extracellular matrix.
    Tissue specificity Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. 
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