IKK gamma Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10845
宿主: Rabbit
反应性: H,M,R
应用: IHC,ELISA
Overview
| Synonyms | IkB kinase associated protein 1, IkB kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma,AMCBX1,FIP 3,FIP-3,FIP3,Fip3p,I kappa B kinase gamma,I-kappa-B kinase subunit gamma,IkB kinase gamma subunit,IkB kinase subunit gamma,IkB kinase-associated protein 1,Ikbkg,IKK-gamma,IKKAP1,IKKG,IMD33,Incontinentia pigmenti,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase gamma,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase of,gamma,Inhibitor of nuclear factor kappa-B kinase subunit gamma,IP,IP1,IP2,IPD2,NEMO,NEMO,NF kappa B essential modifier,NF kappa B essential modulator,NF-kappa-B essential modifier,NF-kappa-B essential modulator,ZC2HC9,IKBKG抗体 |
| Swissprot | Q9Y6K9 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human IKBKG |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC,,1:50-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. |
| Tissue specificity | Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. |
