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KLK2 Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:D-AB-10371L

货期:咨询

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms Glandular kallikrein 2,Glandular kallikrein-1,hGK 1,hGK-1,hK2,Kallikrein 2 prostatic,Kallikrein related peptidase 2, kallikrein, glandular, Kallikrein, prostatic, Kallikrein-2,KLK 2,Klk-2,Klk2,KLK2,KLK2A 2,KLK2A2,MGC12201,Tissue kallikrein 2,Tissue kallikrein-2,Ton
    Swissprot P20151
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant Human KLK2 protein expressed by E.coli
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:1000-1:2000;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted, Extracellular region
    Tissue specificity Highest expression level in prostate gland
    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
    Background This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
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