KLK2 Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10371L
货期:咨询
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | Glandular kallikrein 2,Glandular kallikrein-1,hGK 1,hGK-1,hK2,Kallikrein 2 prostatic,Kallikrein related peptidase 2, kallikrein, glandular, Kallikrein, prostatic, Kallikrein-2,KLK 2,Klk-2,Klk2,KLK2,KLK2A 2,KLK2A2,MGC12201,Tissue kallikrein 2,Tissue kallikrein-2,Ton |
Swissprot | P20151 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human KLK2 protein expressed by E.coli |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:1000-1:2000; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted, Extracellular region |
Tissue specificity | Highest expression level in prostate gland |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
Background | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. |