mTOR Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3580 |
货号:E-AB-63517
宿主: Rabbit
反应性: H,M,R
应用: IHC,IF
Overview
Synonyms | FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS,mTOR,MTOR,MTOR抗体 |
Swissprot | P42345 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant fusion protein of human mTOR (NP_004949.1). |
Application | IHC(Detection kit: E-IR-R213),IF |
Recommended dilution | IHC,, 1:50-1:200;IF,, 1:50-1:200; |
Concentration | 1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Endoplasmic reticulum membrane. Golgi apparatus membrane. Mitochondrion outer membrane. Lysosome. Cytoplasm. Nucleus > PML body. Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to lysosomes depends on amino acid availability and RRAGA and RRAGB. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Background | The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. |
Images
Immunohistochemistry of paraffin-embedded Rat ovary using mTOR Polyclonal Antibody at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded Human tonsil using mTOR Polyclonal Antibody at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver cancer using mTOR Polyclonal Antibody at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded Human placenta using mTOR Polyclonal Antibody at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse liver using mTOR Polyclonal Antibody at dilution of 1:150 (40x lens).
客户发表文献
- 文献: The therapeutic effect of hesperetin on doxorubicin-induced testicular toxicity: Potential roles of the mechanistic target of rapamycin kinase (mTOR) and dynamin-related protein 1 (DRP1)
样品类型: testis tissue - 文献: Effect of PI3K/Akt/mTOR signaling pathway on JNK3 in Parkinsonian rats
样品类型: Tissue homogenate