本公司产品仅供体外研究使用,不用于临床诊断

N-cadherin Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70061

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • 文献(9)
  • Overview

    Synonyms CADH2,Cadherin 2,Cadherin 2 N cadherin neuronal,Cadherin 2 type 1,Cadherin 2 type 1 N cadherin neuronal,Cadherin 2,type 1,N-cadherin (neuronal),Cadherin-2,Cadherin2,Calcium dependent adhesion protein neuronal,CD325,CD325 antigen,CDH2,CDHN,CDw325,CDw325 antigen,N cadherin 1,N-cadherin,NCAD,Neural cadherin,OTTHUMP00000066304,OTTHUMP00000067378,N-cadherin抗体
    Swissprot P19022,P15116,Q9Z1Y3
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:300-1:800;
    Concentration 200 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell junction, Cell membrane, Membrane
    Tissue specificity Highest expression level in cardiac ventricle
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity .

    客户发表文献

    1. 文献: Corneal endothelial cell sheet bioengineering from neural crest cell-derived adipose stem cells on novel thermo-responsive elastin-mimetic dendrimers decorated with RGD
      样品类型: CEC-like cell
    2. 文献: Conjugation of VEGFR1/R2-targeting peptide with gold nanoparticles to enhance antiangiogenic and antitumoral activity
      样品类型: mammary carcinoma tumors (4T1 tumors)
    3. 文献: AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation
      样品类型: DAOY cell
    4. 文献: Cytotoxic Potential of the Marine Diatom Thalassiosira rotula: Insights into Bioactivity of 24-Methylene Cholesterol
      样品类型: A549 cell,MCF7 cell
    5. 文献: Palmitic Acid Inhibits the Growth and Metastasis of Gastric Cancer by Blocking the STAT3 Signaling Pathway
      样品类型: gastric cancer cell
    6. 文献: A novel long noncoding RNA, LOC440173, promotes the progression of esophageal squamous cell carcinoma by modulating the miR‐30d‐5p/HDAC9 axis and the epithelial–mesenchymal transition
      样品类型: Cell lysate
    7. 文献: Anti-tumor and anti-metastatic activity of the FGF2 118-126 fragment dependent on the loop structure
      样品类型: 4T1 cell-xenograft
    8. 文献: Ubenimex Suppresses the Ability of Migration and Invasion in Gastric Cancer Cells by Alleviating the Activity of the CD13/NAB1/MAPK Pathway
      样品类型: MKN-28 cells,MGC-803 cells,BGC-823 cells,SGC-7901
    9. 文献: Dihydrotanshinone-I modulates Epithelial Mesenchymal Transition (EMT) Thereby Impairing Migration and Clonogenicity of Triple Negative Breast Cancer Cells
      样品类型: MDA-MB-468 cells,MDA-MB-231 cells
    如有任何问题,请拨打电话 027-87879180 或填写 在线留言 我们会第一时间联系您。
    ×
    var _hmt = _hmt || []; MIP.watch('count', function () { console.log("sdsfs"); _hmt.push(['_trackEvent', 'consult_mip', 'click', 'detail page']); })