PCNA Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40413
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | ATLD2, cb16, Cyclin, DNA polymerase delta auxiliary protein, etID36690.10, fa28e03, fb36g03, HGCN8729, MGC8367, Mutagen-sensitive 209 protein, OTTHUMP00000030189, OTTHUMP00000030190, PCNA, Pcna/cyclin, PCNAR, Polymerase delta accessory protein,PCNA抗体 |
Swissprot | P12004 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Human Proliferating cell nuclear antigen protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.28mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. |
Images
Western Blot analysis of HepG2, Hela, Raw264.7 Raji and MCF-7 cells using PCNA Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using PCNA Polycloanl Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Mouse testis using PCNA Polycloanl Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Rat testis using PCNA Polycloanl Antibody at dilution of 1:50