Phospho-JAK1 (Tyr1022) Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥630 / ￥1510 / ￥2415 |
货号：E-AB-20913
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF,ELISA
Overview
| Synonyms | JAK 1,JAK 1A,JAK 1B,JAK-1,JAK1,JAK1,JAK1A,JAK1B,Janus kinase 1 (a protein tyrosine kinase),Janus kinase 1,JTK3,Tyrosine protein kinase JAK 1,Tyrosine protein kinase JAK1,Tyrosine-protein kinase JAK1,JAK1 (phospho Tyr1022)磷酸化抗体 |
| Swissprot | P23458 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022 |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF,ELISA |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:50-1:200;ELISA,,1:10000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endomembrane system. Wholly intracellular, possibly membrane associated. |
| Tissue specificity | Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. |
Images
Western Blot analysis of A549 cells with Phospho-JAK1 (Tyr1022) Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer tissue with Phospho-JAK1 (Tyr1022) Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of Mouse liver tissue with Phospho-JAK1 (Tyr1022) Polyclonal Antibody at dilution of 1:200
客户发表文献
- 文献: Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling
样品类型: lung - 文献: Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway
样品类型: Cell culture medium
