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PSMD9 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10569

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC,ELISA

  • 详情
  • Overview

    Synonyms 26S proteasome non ATPase regulatory subunit 9,26S proteasome non-ATPase regulatory subunit 9,26S proteasome regulatory subunit p27,Homolog of rat Bridge 1,MGC8644,p27,Proteasome (prosome macropain) 26S subunit non ATPase 9,Proteasome 26S non ATPase regulatory subunit 9,Proteasome 26S subunit non ATPase 9,PSMD 9,Psmd9,PSMD9,Rpn4,PSMD9抗体
    Swissprot O00233
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human PSMD9
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution WB,,1:500-1:2000;IHC,,1:50-1:200;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytosol,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm,proteasome regulatory particle
    Tissue specificity Expressed in all tissues tested, highly expressed in liver and kidney.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.
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