RICTOR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10904
宿主: Rabbit
反应性: H,M
应用: IHC,ELISA
Overview
| Synonyms | AVO3,AVO3 homolog,DKFZp686B11164,hAVO3,KIAA1999,Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae),mAVO3,MGC39830,PIA,Pianissimo,Rapamycin insensitive companion of mTOR,Rapamycin-insensitive companion of mTOR,Rictor,RICTR,RICTR,RPTOR independent companion of MTOR complex 2,TORC2 specific protein AVO3,RICTOR抗体 |
| Swissprot | Q6R327 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human RICTOR |
| Application | IHC(Detection kit: E-IR-R213),ELISA |
| Recommended dilution | IHC,,1:25-1:200; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Other locations:TORC2 complex |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Rapamycin-insensitive companion of mTOR is a protein that in humans is encoded by the RICTOR gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. |
