TGF β Receptor I Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12904
宿主: Rabbit
反应性: H,M,R
应用: IHC,ELISA
Overview
Synonyms | AAT 5,AAT5,Activin A receptor type II like kinase 53kDa,Activin A receptor type II like kinase,53kD,Activin A receptor type II like protein kinase of 53kD,activin A receptor type II-like kinase,53kDa,activin A receptor type II-like protein kinase of 53kD,Activin receptor like kinase 5,Activin receptor-like kinase 5,ACVRLK 4,ACVRLK4,ALK 5,ALK-5,ALK5,LDS1A,LDS2A,MSSE,Serine/threonine protein kinase receptor R4,Serine/threonine-protein kinase receptor R4,SKR 4,SKR4,TbetaR I,TbetaR-I,TGF beta receptor type 1,TGF beta receptor type I,TGF beta type I receptor,TGF-beta receptor type I,TGF-beta receptor type-1,TGF-beta type I receptor,TGFBR 1,TGFBR1,TGFBR1 protein,TGFR 1,TGFR-1,TGFR1,TGFR1,Transforming growth factor beta receptor 1,Transforming growth factor beta receptor I (activin A receptor type II like kinase,53kD),Transforming growth factor beta receptor I,transforming growth factor,beta receptor 1,transforming growth factor,beta receptor I (activin A receptor type II-like kinase,53kD),Transforming growth factor-beta receptor type I,TGFBR1抗体 |
Swissprot | P36897 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human TGFBR1 |
Application | IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | IHC,,1:50-1:200; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm |
Tissue specificity | Found in all tissues examined, most abundant in placenta and least abundant in brain and heart. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |